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ADHD medications can generally be split into two categories: the stimulants and the non-stimulants. Stimulant drugs used for ADHD include various amphetamines and methylphenidates. Amphetamines and methylphenidates increase the levels of the neurotransmitters, dopamine and norepinephrine in the brain. Both drugs also inhibit monoamine oxidase (MAO), an enzyme that breaks down dopamine and norepinephrine.

ADHD is a psychiatric disorder usually diagnosed during childhood. Children with ADHD are often hyperactive (overactive) and have difficulty paying attention and staying focused on tasks. They may interrupt other people's conversations or be impulsive and impatient. ADHD symptoms can cause problems at home and at school, and often will last into adulthood.Postmarketing reports: Abnormal vision[Ref]

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The material is a white to light tan/light pink powder with a molecular formula of C6H6N6O2 and a molecular weight of 194.15. The molecule is stable at acidic pH ( < 5) and labile at pH > 7; hence TEMODAR can be administered orally and intravenously. The prodrug, temozolomide, is rapidly hydrolyzed to the active 5-(3-methyltriazen-1-yl) imidazole-4-carboxamide (MTIC) at neutral and alkaline pH values, with hydrolysis taking place even faster at alkaline pH.

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